Why is this study being done?
We are enrolling men, women, and couples who have experienced pregnancy loss. This data will help us find patterns in recurrent pregnancy loss and better understand your journey. By providing us with your medical history and DNA samples, we will be able to investigate genes that may be associated with pregnancy loss.
Am I eligible to participate?
Please review the individual criteria for the HOPE registry, Genetic Sequencing, and Pre-pregnancy cohort to determine your eligibility.
What will happen if I decide to participate in this study?
Once enrolled into the HOPE registry, you will have the option to learn about specific studies for which you may be eligible. One study will use Genetic sequencing from parents and miscarriage tissue. Couples participating in this study will have the option of receiving the results of their genetic studies. For couples planning a pregnancy, you may be eligible to enroll in the Pre-pregnancy cohort.
Will I receive the results of my sample analysis?
Enrolled subjects may choose to receive the results of their trio analysis. These results will only be provided if genetic variants are found for which interventions are possible.
What is the time commitment required to participate in the study?
For patients enrolled in the HOPE registry, your participation may take between 60-120 minutes depending on the surveys you are asked to complete. The sample collection procedure should only take 5-10 minutes after your routine procedure.
If you participate in the pre-pregnancy cohort, your participation may take between 60-120 minutes depending on the number of blood draws. You may then receive a link to complete a 10-minute survey every 6 months for up to 5 years.
Will I be compensated?
If you complete periodic online surveys as frequently as every 6 months for up to 5 years from enrollment, you will receive a $10 incentive for each survey completed. If patients in the sequencing cohort are willing to provide subsequent pregnancy outcomes by online surveys, you may receive an additional $10 for each survey completed.
For patients in the pre-pregnancy cohort, you will receive a $40 incentive for each blood draw, a $40 incentive if outside medical records are requested and a $10 incentive for completing surveys about future pregnancies for up to 5 years.
How do I enroll?
A research coordinator will be in touch regarding participation in the study
How do I contact the study team?
You can contact the study team by clicking below, or emailing [email protected]
Can I review the informed consent before deciding to participate?
Yes! Please download a copy of our informed consent for your review. A study coordinator would be happy to review with you if you have any questions or clarifications.
How are the samples collected?
The samples will be collected as a part of your routine procedure at the gynecological office.
What are the side effects or risks from being in the study?
If you consent to donate blood, the needle stick may hurt. There is a small risk of bruising and fainting, and a rare risk of infection.
Don’t see your question above? Email us at [email protected] and the study team will be happy to answer your question!